[HTML][HTML] What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2?

M Hellerstein - Vaccine: X, 2020 - Elsevier
immunity and cell mediated immunity, particularly from CD8 T-cells, play key roles in
vaccine-induced protective immunityT-cell responses have been better markers than antibody …

T cell immunity to COVID-19 vaccines

EJ Wherry, DH Barouch - Science, 2022 - science.org
memory T cells contribute to protective immunity to SARS-CoV-2? In cancer patients with B
cell deficiencies that experience COVID-19, CD8 + T cellbetter understanding of which T cell

BNT162b2 vaccination induces durable SARS-CoV-2–specific T cells with a stem cell memory phenotype

G Guerrera, M Picozza, S D'Orso, R Placido… - … immunology, 2021 - science.org
… as indicators of protective immunity (19–21) and represent the final output of a coordinated
… number of AIM + CD4 + cells 21 days after priming was the best predictor of anti-RBD levels …

Covid-19 vaccines: delivering protective immunity

HF Sewell, RM Agius, D Kendrick, M Stewart - bmj, 2020 - bmj.com
… results from phase III vaccine trials, and previous … memory T cell responses to the vaccines,
along with B cell antibody responses, should provide good and possibly enduring immunity

[HTML][HTML] B cell memory: building two walls of protection against pathogens

M Akkaya, K Kwak, SK Pierce - Nature Reviews Immunology, 2020 - nature.com
… To obtain the best experience, we recommend you use a more … recent vaccines, such as
those that elicit protective immunity to … T cell-independent antigens can generate memory B cells

[PDF][PDF] Humoral and cellular immune memory to four COVID-19 vaccines

Z Zhang, J Mateus, CH Coelho, JM Dan… - Cell, 2022 - cell.com
… of T cell, B cell, and antibody responses to diverse vaccines in humans are likely to be
informative for understanding protective immunity … To the best of our knowledge, this is the most

Low-dose mRNA-1273 COVID-19 vaccine generates durable memory enhanced by cross-reactive T cells

J Mateus, JM Dan, Z Zhang, C Rydyznski Moderbacher… - Science, 2021 - science.org
… and Moderna indicate protective immunity of 91 and 93%, … better appreciate (i) the
mechanisms of protective immunity provided by the vaccines, (ii) the durability of immune memory

[HTML][HTML] Targeting memory T cell metabolism to improve immunity

M Corrado, EL Pearce - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
… advances in defining memory T cell metabolism and how metabolism of these cells might
be … long-term might be a critical step in the development of efficient T cell–targeted vaccines. …

[HTML][HTML] CD4+ T cell help creates memory CD8+ T cells with innate and help-independent recall capacities

T Ahrends, J Busselaar, TM Severson, N Bąbała… - Nature …, 2019 - nature.com
… To obtain the best experience, we recommend you use a more up … T cell help delivered
during priming impacts CD8 + T cell memory, we used a mouse model of therapeutic vaccination. …

[HTML][HTML] The T cell immune response against SARS-CoV-2

P Moss - Nature immunology, 2022 - nature.com
… To obtain the best experience, we recommend you use a more … Current COVID-19 vaccines
elicit robust T cell responses … has led to concern that protective immunity against SARS-CoV-…